By Debo Dutta, Chief AI Officer, Nutanix
As we prepare for AMD Advancing AI 2026, the conversation around enterprise AI is fundamentally shifting. We are moving from isolated experimentation to large-scale execution. At Nutanix, we've always believed that the infrastructure you choose dictates the intelligence you can build.
We are moving beyond simple chat interfaces into the era of Agentic AI - systems where autonomous agents retrieve context, reason across multiple steps, interact with tools, and run continuously to solve complex business problems. But as these agents run 24/7, a critical question emerges for enterprise IT leaders: Are you going to own your intelligence, or rent it?
When you rent intelligence from public API providers, the tokenomics can quickly become unsustainable. The math has fundamentally changed. What used to consume a couple thousand tokens per question now consumes 20,000 or more as sophisticated sub-agents write code, run tests, and check their own work. As your agents consume and generate millions of tokens daily to perform routing, validation, and execution tasks, the financial reality of rented infrastructure becomes a massive bottleneck to scale.
Owning your intelligence doesn't mean completely abandoning frontier models; it means taking control of your routing, your volume, and your costs. We advocate for a two-tier intelligence strategy.
By utilizing an agent gateway that sits securely between your applications and your models, you can route requests intelligently, balance load, manage keys, and enforce policy across providers. This allows you to leverage expensive frontier models for a small fraction of tasks that require complex, edge-case reasoning. The vast majority of your high-volume tasks - data retrieval, standard code generation, formatting, and continuous agent validation - are routed to highly optimized models running securely on your private infrastructure.
To make this two-tier Agentic AI model sustainable, enterprises need an AI factory - a dedicated environment designed to continuously turn data into high-value tokens and actionable intelligence.
At AMD Advancing AI 2026, we are demonstrating how to build this foundation. By combining the Nutanix Cloud Platform and Nutanix Enterprise AI solutions with high-performance AMD EPYC™ processors and GPU integration, specifically the AMD Instinct™ MI355X accelerators, we are delivering a full-stack solution designed to give enterprises greater control over their AI workloads.
This joint architecture allows you to:
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